I’ve been having a nasty rash (hives or eczema) on my thighs for weeks which gets so itchy during bedtime that I have trouble sleeping. So far only a good scratch would relieve the itch…but then, scratching prevents the skin from healing and thats why its been going on for soooo many weeks already!
Searching online, I finally found a remedy that FINALLY seems to work. Applying heat to the area seems to work really well. I used a copper cup filled with very hot water. As hot as I could take without it being painful/burning. At first, there was a great itch when the skin comes in contact with the heat. It felt like “pin pricks of itchiness” erupting and I just had to bear it. That’s because the excessive heat triggered the release of histamines by mast cells all at once. Then after a while, the itch subsided. Once all the histamines have been released, the body needs a few hours to replenish those histamines. Hence, temporary relief!!
According to the internet, it works on mosquito bites and all sorts of itches too 
Anyway, from what I learnt from Immunology, igE will bind strongly to mast cells and trigger the release of histamine. So although the histamine has been released, the IgE is STILL binding to the mast cells and will cause the release of more histamine later on! I hate this Hypersensitive Type I reaction!! (Better check whether Type I is correct)
Hopefully tonight I don’t scratch and the rash will heal. Such a long post about a little rash, but its really been bugging me for the last few weeks!
